Monday March 2, 2009
Q: Why oxygen should be administered to every patient with suspected PE, even when the arterial PO2 is perfectly normal?
Answer; Oxygen should be administered to every patient with suspected PE, even when the arterial PO2 is perfectly normal, because increased alveolar oxygen may help to promote pulmonary vascular dilatation.
Monday, March 2, 2009
Sunday, March 1, 2009
Sunday March 1, 2009
Q: In which clinical condition, usually a lower maintenance dose of warfarin is required?
Answer; In thyrotoxic atrial fibrillation
The recommended loading dose of warfarin in thyrotoxic atrial fibrillation is similar to euthyroid patients, but a lower maintenance dose is required because of accelerated clearance of vitamin K-dependent clotting factors.
Reference:
Shenfield GM. Influence of thyroid dysfunction on drug pharmacokinetics. Clin Pharmacokinet. 1981;6:275-297
Q: In which clinical condition, usually a lower maintenance dose of warfarin is required?
Answer; In thyrotoxic atrial fibrillation
The recommended loading dose of warfarin in thyrotoxic atrial fibrillation is similar to euthyroid patients, but a lower maintenance dose is required because of accelerated clearance of vitamin K-dependent clotting factors.
Reference:
Shenfield GM. Influence of thyroid dysfunction on drug pharmacokinetics. Clin Pharmacokinet. 1981;6:275-297
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